Research Projects

Ongoing Projects

Academic - Industry Collaborative Project Funded by Govt. of India

Name of the Project	Name of PI/Co-PI	Duration	Name of the funding Agency	Amount Sanctioned(Rs.)
Opportunities to Explore Microbial Diversity for industrial important microbial products	PI: Prof. Neelu Nawani Dr. Amit Ranjan DYPBBI PI: Dr. Yasmin Mirza Dr. Rishi Jain Praj Industries Ltd. Pune	2018-2020	Department of Biotechnology New Delhi. (DBT)	8.0152 Cr

International Projects

Title of Research project	DPU Investigator/ Collaborator	Foreign Investigators/ Collaborators	Funding agency	Total Grant value, Duration and grant amount for DPU
Comparative study of actinomycetes biodiversity in India and Tunisia: investigation of biotechnological enzymes and biological activities	Dr. Neelu Nawani and Dr. M. B. Khetmalas	Dr. Sofiane Ghorbel and Dr. Noomen Hmidet, Ecole Nationale D'Ingenieurs de Sfax, Tunisia	Indo-Tunisian Collaborative project Department of Science and Technology, Government of India	Rs. 24,39,000 March 2013 to Feb 2016
The emergence and persistence of novel resistance to 3^rd generation cephalosporins and carbapenem in bacteria in the environment	Dr. Neelu Nawani	Dr. Jana Jass, University of Orebrö, Sweden and Dr. Abul Mandal, University of Skövde, Sweden	FORMAS, Swedish Research Council, Sweden	SEK 1,70,000 Jan 2015 to Dec 2016

National Projects

Title of Research project	DPU Investigator/ Collaborator	Year of Grant Received and Duration	Funding agency	Grant Sanctioned (in lakhs)
A study to generate proof of concept on metabopsy of discarded milk teeth and nail clippings for the early diagnosis of inherited metabolic disorders (IMD)”	Prof. Nilesh K Sharma (PI) Co-PIs Prof. Sachin C Sarode Prof. Shraddha Salunkhe	2023	ICMR-DHR	35,00,000 lakhs 2 years
Comprehensive evaluation of long non-coding RNAs in oral squamous cell carcinoma diagnosis and therapy	Dr. Subhayan Sur	2022	DBT (Ramalingaswami Fellowship )	1,23,60,000 lakhs 5 years
Investigating the role of a tomato membrane bound NAC TF (SlNACMTF3) in shaping antiviral immune response against tomato leaf curl virus.	Dr. Supriyo Chowdhury	2022	DST SERB SRG	32,83, 000 lakhs 2 years
Preparation of Next Generation Nanovaccine unsing multifunctional glycans for cancer immunotherapy	Dr. Rajesh Kumar Gupta	2021	India Japan Science and Technology Cooperation	2,98,400 lakhs 3 years
Segregation and management of laboratory wastes for resource recovery and value addition	PI: Dr. Viniti Vaidya DYPBBI Co-PI: Dr. Neelu Nawani, Industry Partner: Agroinnovations India Private Limited	3 years	Department of Science and Technology, (DST), Technology Development and Transfer (TDT) Division	50,18,800 L
A BioeStudies on the protection of DNA from oxidative damage, by chito-oligosaccharides, biologically extracted from seafood waste electrochemical system for sequestration of carbondioxide	Dr. Neelu Nawani	Nil	Department of Science and Technology, Government of India	Rs. 27,32,000
Name of the Project	Name of PI/Co-PI	Duration	Name of the funding Agency	Amount Sanctioned(Rs.)
A study to understand drug induced acute kidney injury using bioinformatics approach	PI: Dr. Vasudha S Satalkar (PI) Dr. K. V. Swamy (Mentor)	2018-2020	DST-WOS-A	Rs. 30, 45, 000
Opportunities to Explore Microbial Diversity for industrial important microbial products	PI: Prof. Neelu Nawani	2017-2019	DBT	Rs. 8,01,52,000
Harnessing the potential of neo-glycoconjugates in antigen cross-presentation for effective CD8+T cell response in cancer.	PI: Dr. Rajesh K Gupta	2017-2019	DST-SERB	Rs. 40,02,027
"Design, synthesis and evaluation of novel structural analogs of natural products as a selective modulator of PPAR pathway for lung cancer therapy	PI: Dr. Soumya Basu Co-PI: Dr.K.V.Swamy	2017-2019	DST-SERB	Rs. 48,00,000
Molecular modelling and docking studies of Deguelin and its derivatives with cell arrest, apoptosis and anti- angiogenesis pathway proteins n cancer cell signaling pathways	PI: Dr. K. V Swamy	2016-2018	DST-SERB	Rs. 17,64,250

DPU Projects

Title of the Project	Principal-Investigator	Total Sanctioned amount for recurring (Glassware, Chemicals field work, stationary, etc.)	Year
In-silico–based Comprehensive analysis and exploration of multi-omics epilepsy datasets: from potential biomarkers to drug targets	Dr. Dimple Davray	5,00,000/-	2024-25
Assessment of the anti-metastatic potential of repurposed drugs for modulation of exosomal miRNAs in triple-negative breast cancer	Dr. Amit Ranjan	5,00,000/-	2024-25
Validation of indigenous exosome isolation kit (Ex-O-Ex kit) and exploring its application for understanding global transcriptome of triple negative breast cancer- associated non-coding RNA	Dr. Soumya Basu	5,00,000/-	2024-25
Development of biosensors for detection of biological entities	Amit Kumar Singh	5,00,000/-	2024-25
Innovative technique for lactose detection :- Development of real time health monitoring Nanobiosensors	Dr. Latika Shendre	5,00,000/-	2024-25
Identification of gut microbiome signature in multiple sclerosis patients in Western Indian population	Dr. Ajit Kulkarni	5,00,000/-	2024-25
Deciphering the effect of manipulation of TGF-β1-YAP1-TEAD signaling axis in pulmonary fibrosis	Dr. Nilay Mitash	5,00,000/-	2024-25
Investigation of the morpho-physiological and molecular response of rice (Oryza sativa) to salinity stress	Dr. Suhasini B	5,00,000/-	2024-25
Investigating the role of ABCG5 transporters in air channel formation and hypoxia stress tolerance	Dr. Ganesh m. Nawkar	5,00,000/-	2024-25
Sensing the heterogeneity in glycan composition to enhance targeting of c-type lectin receptors on antigen presenting cells and induction of antigen specific cellular immunity	Dr. Rajesh Kumar Gupta	5,00,000/-	2024-25
Studies on the protein interactions of Grainyhead-like transcription factors in idiopathic pulmonary fibrosis and nuclear organization	Dr. Satish Sasikumar	5,00,000/-	2024-25

Completed Projects

International Projects

Title of Research project	Investigator	Foreign Investigators/Collaborators	Funding agency	Total Grant value, Duration and grant amount for DPU
Bioremediation of toxic metals and other pollutants for protecting human health and ecosystem	Dr. Neelu Nawani	Dr. Abul Mandal, University of Skövde, Sweden Dr. B. P. Kapadnis, Department of Microbiology, University of Pune	Swedish International Development Cooperation Agency, Sweden	SEK 45,00,000/- Dec 2010- Dec 2013
Identifying novel biomarkers of COPD and design of innovative preventive and therapeutic strategies targeted for the benefit of Indian population	Dr. M. B. Khetmalas, Dr. Neelu Nawani Dr. Tushar Sahasrabuddhe	Dr. Cecilia Eriksson and Dr. Abul Mandal, University of Skövde, Sweden	Swedish International Development Cooperation Agency, Sweden	SEK 21,00,000 July 2012- April 2014

National Projects

Title of Research project	DPU Investigator/ Collaborator	Foreign Investigators/ Collaborators	Funding agency	Total Grant value, Duration
A Bioelectrochemical system for sequestration of carbon dioxide	Dr. M. B. Khetmalas and Dr. Neelu Nawani	Nil	Department of Science and Technology, Government of India	Rs. 38,04,570
Name of the Project	Name of PI/Co-PI	Duration	Name of the funding Agency	Amount Sanctioned(Rs.)
Exploitation of abnormal DNA repair in cancer as a strategy for cancer therapy	PI: Dr. Nilesh K. Sharma	2014-2017	DST-SERB	Rs. 22,63,000

DPU Projects

Title of Research project	Principal Investigator	Co-Investigator	Research Grant
Effect of Ethanol on carbohydrate, Proteins & membrane lipids of Saccharomyces sp.	Dr. Manjusha Dake	Nil	Rs.1,40,000
Studies on Stevia with special reference to micropropagation, mutation and phytochemistry	Dr. M. B. Khetmalas	Snehal Pande	Rs. 11,11,000
Steroidal motifs as anticancer agents	Dr. Vidya Kothekar	K. Swamy	Rs. 3,00,000
Phyto capping Technique to Reduce Methane Emission from Municipal Landfill sites.	Dr. Vrushali Ganesh Gadekar (Kanavade)	Nil	1487227
Studies on post harvest life of cut Gerbera flowers: Physio biochemical and molecular studies of various metabolic changes during senescence	Dr. Minal Wani	Nil	30000
Propagation and flowering of orchids using artificial soil abatement	Dr. Neelu Nawani	Nil	350000
Design and development of inhibitors for Malaria	Dr. K. V. Swamy	Nil	326000
Effect of ethanol on carbohydrate, lipids and proteins of Saccharomyces species	Dr. Manjusha Dake	Nil	1437500
Investigation of chemical constituents and antibacterial activity of Coriandrum sativum seeds	Dr. Supriya Vinayak Kore	Nil	200000
Identifying novel biomarkers of chronic obstructive pulmonary disease (COPD) for its early detection and prognosis	Dr. Neelu Nawani	Nil	300000
Mitochondrial marker screening of GDM and post-partum T2DM Indian patients using FACS and Confocal microscopy technique	Dr. Nilesh Kumar Sharma	Nil	500000
Deciphering Mechanism of Anticancer Activity of Plumbagian on Oral Carcinoma cell line	Dr. Soumya Basu	Nil	500000
To study the anticancer effects of Aegle marmelos extracts on breast cancer cells and colorectal carcinoma cells	Dr. Mitali Tiwari	Dr. Soumya Basu	500000
Development of Natural Immunomodulators to Enhance Immuno-response via Molecular Nutrition from Tridax procumbens seed extract.	Dr. Aher Vaibhav Dagaji	Dr. Neelu Nawani	500000
Development of novel particle mediated vaccine delivery system	Dr. Rajesh Kumar Gupta	Nil	200000
Evaluation of antimicrobial agent as food preservative and treatment of food borne diseases	Dr. Supriya V Kore	Nil	180000
Role of CD63 and its glycosylation in regulating cancer metastasis	Dr. Amit Ranjan	Nil	200000
Development of a biomaterial matrix for the reduction of cholesterol in milk (and thereby milk products) and eggs	Dr. Manisha Deshpande	Nil	85500
Investigating landscape of crosstalk between ATM kinase and DNA ligase III in breast carcinoma cells	Dr. Nilesh Sharma	Nil	2350000
Effect of mutation of the transmembrane polar residues of CD151 on its subcellular localization and invasion	Dr. Amit Ranjan	Nil	1500000
In Vitro safety evaluation of cholesterol depleted milk	Dr. Manisha Deshpande	Nil	1450000
Evaluation of chemo preventive/anti-cancer activity of lactic acid bacteria on colon carcinoma	Dr. Soumya Basu	Nil	2000000
Screening of lactic acid bacteria for characteristic human and plant probiotic properties	Dr. Neelu Nawani	Nil	1340000
Bioprospecting of beneficial bacterial endophytes from endemic plants in western ghats of India	Dr. Rachana Pandey	Nil	945000
In vitro enzymatic studies on protease inhibitors originating from plant source to analyze their antimicrobial potential	Mrs. Ashwini Puntambekar	Nil	275000
Exploring the potential of agricultural and domestic lignocellulosic feedstock for microbial production of bioethanol	Dr. G. D. Tandon	Mr. Amol Salagare	690000
Harnessing the potential of antigen presentation n immunotherapy	Dr. Rajesh Gupta	Nil	2392000

Sr. No.	Name of the Project	Name of the PI/Co-PI	Sanction Amount Rs.	Date of Sanction
1.	Development of spheroid cultures from cancer cell lines for drug screening	Dr. Soumya Basu	3,00,000	2021
2.	Statistical Investigation for the treatment of Dairy wastewater by employing microalgae and membrane technology	Dr. Gayatri Gera	2,00,000	2021
3.	Enhanced active phytoconstituent projection from Tinospora cordifolia via in vitro cell regeneration and its computational interaction studies against SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2)	Dr. Jyoti Deshpande	3,00,000	2021
4.	Study on biomarkers in biological fluids and materials from oral cancer and precancerous patients	Dr. Nilesh Kumar Sharma	3,00,000	2021
5.	Cultivation studies of micro algae using industrial effluents	Dr. Allika Sailaja	1,50,000	2021
6.	Avapro: An ecofriendly probiotic formulation for discouraging the use of antibiotics and chemical growth hormones in poultry feed	Dr. Manisha Junnarkar	500000	2020
7.	Molecular and genetics analysis of Granyhead like protein in idepathic pulmonary fibrosis and neuclear Organization	Dr. Satish Sasikumar	320000	2019
8.	Development of molecular markers for assessment of genetic diversity among the ecotype of Stevia Rebaudiana	Dr. Minal Wani	300000	2019
9.	Biosynthesis and characterization of nanoperticles using pant extract of tagets patula and Lantana Camara and its anti levae activity against mosquito	Dr. Huda Afreen	674000	2019
10.	Characterization and biosyntehsis of fructans : Prebiotic health improving Compound	Dr. Viniti Vaidya	300000	2019
11.	Characterization of nanostructure polymer to develop Scafford for tissue engineering	Dr. Swapnil Gaikwad	300000	2019
12.	Formulation and biochemical assessment of minimal sugar arishta during fermentative maturation	Dr. Minal Wani	700000	2019
13.	Influence of chemical contaminants in natural water bodies on the emergence of antibiotic resistance in Escherichia coli	Dr. Neelu Nawani	2000000	2017
14.	Quality improvement and increase in shelf life of different food products using essential oil	Dr. Supriya Kore	600000	2017
15.	Virtual screening for novel quorum sensing inhibitors: Anti-virulence therapy against Pseudomonas aeruginosa	Dr. Sarika V Pawar	600000	2017
16.	In silico and in vivo studies to look for Aromatase inhibitors for cancer therapy	Dr. Shuchi Nagar	1066000	2017
17.	Management of biological waste (laboratory media, garden waste and kitchen waste) generated on campus at Tathawade)	Dr. Neelu Nawani	300000	2015

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